2 papers
cs.LG2026
Disease Is a Spectral Perturbation
John D. Mayfield, Matthew S. Rosen
We propose a novel method of understanding disease transformation from a healthy baseline with biomarker-level explainability. By modeling the biomarker covariance matrices of heal…
q-bio.OT2025
Frequency-Domain Analysis of Time-Dependent Multiomic Data in Progressive Neurodegenerative Diseases: A Proposed Quantum-Classical Hybrid Approach with Quaternionic Extensions
John D. Mayfield
Progressive neurodegenerative diseases, including Alzheimer's disease (AD), multiple sclerosis (MS), Parkinson's disease (PD), and amyotrophic lateral sclerosis (ALS), exhibit comp…