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physics.bio-ph2024
Amino Acids and Their Biological Derivatives Modulate Protein-Protein Interactions In an Additive Way
Xufeng Xu, Francesco Stellacci
Protein-protein interactions (PPI) differ when measured in test tubes and cells due to the complexity of the intracellular environment. Free amino acids (AAs) and their derivatives…
physics.bio-ph2024
Liquid-liquid phase separation of proteins is modulated by amino acids in vitro and in vivo by regulating protein-protein interactions
Xufeng Xu, Aleksander A. Rebane, Laura R. Julia +3
Liquid liquid phase separation (LLPS) of proteins is an intracellular process that is widely used by cells for many purposes. In living cells (in vivo), LLPS occurs in complex and…