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physics.bio-ph2003
Simulations of Oligomeric Intermediates in Prion Diseases
David L. Mobley, Daniel L. Cox, Rajiv R. P. Singh +2
We extend our previous stochastic cellular automata based model for areal aggregation of prion proteins on neuronal surfaces. The new anisotropic model allow us to simulate both st…
physics.bio-ph2003
Modeling Amyloid Beta Peptide Insertion into Lipid Bilayers
David L. Mobley, Daniel L. Cox, Rajiv R. P. Singh +2
Inspired by recent suggestions that the Alzheimer's amyloid beta peptide (A beta) can insert into cell membranes and form harmful ion channels, we model insertion of the 40 and 42…