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physics.bio-ph2026
FILM: Mapping organellar metabolism by mid-infrared photothermal modulated fluorescence
Jianpeng Ao, Jiaze Yin, Haonan Lin +10
Metabolism unfolds within specific organelles in eukaryotic cells. Lysosomes are highly metabolically active organelles, and their metabolic states dynamically influence signal tra…
physics.bio-ph2026
Label-free Imaging of Single-Biomolecule Structure and Interaction by Stimulated Raman Photothermal Encoded Scattering
Pin-Tian Lyu, Yifan Zhu, Qing Xia +8
Current single molecule methods either rely on fluorescence or lack chemical information. Here we report stimulated Raman photothermal encoded scattering (SRPSCAT) microscopy for q…