3 papers
stat.ME2026
A Model-Robust G-Computation Method for Analyzing Hybrid Control Studies Without Assuming Exchangeability
Zhiwei Zhang, Peisong Han, Wei Zhang
There is growing interest in a hybrid control design for treatment evaluation, where a randomized controlled trial is augmented with external control data from a previous trial or…
stat.ME2025
An adaptive design for optimizing treatment assignment in randomized clinical trials
Wei Zhang, Zhiwei Zhang, Aiyi Liu
The treatment assignment mechanism in a randomized clinical trial can be optimized for statistical efficiency within a specified class of randomization mechanisms. Optimal designs…
stat.ME2025
Optimal Treatment Allocations Accounting for Population Differences
Wei Zhang, Zhiwei Zhang, Aiyi Liu
The treatment allocation mechanism in a randomized clinical trial can be optimized by maximizing the nonparametric efficiency bound for a specific measure of treatment effect. Opti…