3 papers
stat.ME2026
Communicating results in trials with multiple hypotheses or adaptive design features
Elina Asikanius, Marcel Wolbers, Mouna Akacha +8
Over time, clinical trials have increasingly incorporated complex design and analysis elements such as interim analyses, adaptations, multiple endpoints, and sophisticated multipli…
stat.AP2025
A hierarchical modelling approach for Bayesian Causal Forests on longitudinal data: A Case Study in Multiple Sclerosis Clinical Trials
Emma Prevot, Dieter A. Häring, Thomas E. Nichols +2
Long-running clinical trials offer a unique opportunity to study disease progression and treatment response over time, enabling questions about how and when interventions alter pat…
stat.ME2025
Simplifying Causal Mediation Analysis for Time-to-Event Outcomes using Pseudo-Values
Alex Ocampo, Enrico Giudice, Dieter A. Häring +3
Mediation analysis for survival outcomes is challenging. Most existing methods quantify the treatment effect using the hazard ratio (HR) and attempt to decompose the HR into the di…