2 papers
stat.ME2026
BOIN Designs for Dose Escalation With Selected Dose Combinations in Oncology Phase I Trials
Yuxuan Chen, Haiming Zhou, Keiko Nakajima +1
In phase I dose escalation studies for dual-agent combinations, at least one drug often has an established monotherapy dose. Consequently, substantial prior clinical safety data of…
stat.AP2025
A Bayesian Basket Trial Design Using Local Power Prior
Haiming Zhou, Rex Shen, Sutan Wu +1
In recent years, basket trials, which allow the evaluation of an experimental therapy across multiple tumor types within a single protocol, have gained prominence in early-phase on…