activity
20042024
most citedWhat drives amyloid molecules to assemble into oligomers and fibrils?

143 citations · 271 across the 12 of their papers we have counts for

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Showing cond-mat.softShow all

8 papers · 1 filter

cond-mat.soft2024

Competing addition processes give distinct growth regimes in the assembly of 1D filaments

Sk Ashif Akram, Tyler Brown, Stephen Whitelam +3

We present a model to describe the concentration-dependent growth of protein filaments. Our model contains two states, a low entropy/high affinity ordered state and a high entropy/…

cond-mat.soft2019★ 4 cited

Effects of non-pairwise repulsion on nanoparticle assembly

Sawyer S. Hopkins, Amitabha Chakrabarti, Jeremy D. Schmit

Electrostatic interactions provide a convenient way to modulate interactions between nanoparticles, colloids, and biomolecules because they can be adjusted by the solution pH or sa…

cond-mat.soft2011

Intermolecular adhesion in conjugated polymers: The role of the band gap and solitonic excitations

Jeremy D. Schmit, Alex J. Levine

Conjugated polymers are soft, one-dimensional conductors that admit complex interactions between their polymeric, conformational degrees of freedom and their electronic ones. The p…

cond-mat.soft2010★ 143 cited

What drives amyloid molecules to assemble into oligomers and fibrils?

Jeremy Schmit, Kingshuk Ghosh, Ken Dill

We develop a general theory for three states of equilibrium of amyloid peptides: the monomer, oligomer, and fibril. We assume that the oligomeric state is a disordered micelle-like…

cond-mat.soft2010★ 18 cited

Electrostatics and aggregation: how charge can turn a crystal into a gel

Jeremy Schmit, Stephen Whitelam, Ken Dill

The crystallization of proteins or colloids is often hindered by the appearance of aggregates of low fractal dimension called gels. Here we study the effect of electrostatics upon…

cond-mat.soft2007★ 38 cited

Diffusion limited reactions in confined environments

Jeremy D. Schmit, Ercan Kamber, Jané Kondev

We study the effect of confinement on diffusion limited bimolecular reactions within a lattice model where a small number of reactants diffuse amongst a much larger number of inert…

cond-mat.soft2006★ 3 cited

Intermolecular Adhesion in Conjugated Polymers

Jeremy D. Schmit, Alex J. Levine

Conjugated polymers are observed to aggregate in solution. To account for this observation we propose a inter-chain binding mechanism based on the intermolecular tunneling of the d…

cond-mat.soft2004★ 1 cited

Intermolecular adhesion in conducting polymers

Jeremy D. Schmit, Alex J. Levine

We analyze the interaction of two conducting, charged polymer chains in solution using a minimal model for their electronic degrees of freedom. We show that a crossing of the two c…