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q-bio.CB2018★ 82 cited
Balance of Mechanical Forces Drives Endothelial Gap Formation and May Facilitate Cancer and Immune-Cell Extravasation
Jorge Escribano, Michelle B. Chen, Emad Moeendarbary +5
The formation of gaps in the endothelium is a crucial process underlying both cancer and immune cell extravasation, contributing to the functioning of the immune system during infe…
q-bio.CB2014★ 9 cited
Remodeling of Fibrous Extracellular Matrices by Contractile Cells: Predictions from Discrete Fiber Network Simulations
Abhilash Nair, Brendon M. Baker, Britta Trappmann +2
Contractile forces exerted on the surrounding extracellular matrix (ECM) lead to the alignment and stretching of constituent fibers within the vicinity of cells. As a consequence,…