3 papers
stat.ME2026
A Zero-Inflated Beta Mixture Model for Marginal Mediation Analysis with Compositional Microbiome Mediators
Seungjun Ahn, Quran Wu, Alicia Yang +1
The role of the microbiome in disease pathogenesis is an emerging field with strong evidence suggesting that dysbiosis is associated with precancerous and cancerous states. Microbi…
stat.ME2026
A Quasi-Regression Method for the Mediation Analysis of Zero-Inflated Single-Cell Data
Seungjun Ahn, Donald Porchia, Panos Roussos +3
Recent advances in single-cell technologies have advanced our understanding of gene regulation and cellular heterogeneity at single-cell resolution. Single-cell data contain both g…
stat.ME2025
Causal Mediation Analysis for Zero-inflated Mixture Mediators
Meilin Jiang, Seonjoo Lee, A. James O'Malley +2
Causal mediation analysis is an important statistical tool to quantify effects transmitted by intermediate variables from a cause to an outcome. There is a gap in mediation analysi…