53 citations · 189 across the 9 of their papers we have counts for
3 papers · 1 filter
Robustness of synthetic oscillators in growing and dividing cells
Joris Paijmans, David K Lubensky, Pieter Rein ten Wolde
Synthetic biology sets out to implement new functions in cells, and to develop a deeper understanding of biological design principles. In 2000, Elowitz and Leibler showed that by r…
A Thermodynamically consistent model of the post-translational Kai circadian clock
Joris Paijmans, David K Lubensky, Pieter Rein ten Wolde
The principal pacemaker of the circadian clock of the cyanobacterium S. elongatus is a protein phosphorylation cycle consisting of three proteins, KaiA, KaiB and KaiC. KaiC forms a…
Period Robustness and Entrainability of the Kai System to Changing Nucleotide Concentrations
Joris Paijmans, David K Lubensky, Pieter Rein ten Wolde
Circadian clocks must be able to entrain to time-varying signals to keep their oscillations in phase with the day-night rhythm. On the other hand, they must also exhibit input comp…