2 papers
cs.LG2026
Purely Agent-Driven Black-Box Optimization for Biological Design
Natalie Maus, Yimeng Zeng, Haydn Thomas Jones +11
Many key challenges in biological design -- such as small-molecule drug discovery, antimicrobial peptide development, and protein engineering -- can be framed as black-box optimiza…
cs.LG2026
PepCompass: Navigating peptide embedding spaces using Riemannian Geometry
Marcin Możejko, Adam Bielecki, Jurand PrÄ dzyÅski +10
Antimicrobial peptide discovery is challenged by the astronomical size of peptide space and the relative scarcity of active peptides. Generative models provide continuous latent "m…