7 papers
Finite-Time Optimal Control by Noisy Traps
Luca Cocconi, Henry Alston, Thibault Bertrand
The optimal control of passive systems in equilibrium typically favours quasistatic (infinite-time) protocols. We show that a breakdown of quasistatic optimality occurs when the co…
Neutralization titers reveal the structure of polyclonal antibody responses
Henry Alston, Thierry Mora, Aleksandra M. Walczak
The composition of a polyclonal antibody response is hard to measure experimentally but contains vital information about the robustness of immunity. Here, we argue that the statist…
Theoretical limits for sensing through phase separation
Henry Alston, Mason Rouches, Arvind Murugan +2
Biomolecular condensates form on timescales of seconds in cells upon environmental or compositional changes. Condensate formation is thus argued to act as a mechanism for sensing s…
Controlling the Glass Transition through Active Fluctuating Interactions
Emir Sezik, Henry Alston, Thibault Bertrand
Fluctuating pairwise interactions are understood to drive fluid-like states in dense biological systems. These states find a broad range of functionalities, such as directing growt…
Stochastic Forces Enhance Tracer Diffusion in Non-motile Active Matter
Henry Alston, Raphael Voituriez, Thibault Bertrand
Stochasticity is a defining feature of the pairwise forces governing interactions in biological systems-from molecular motors to cell-cell adhesion-yet its consequences on large-sc…
Conditional splitting probabilities for hidden-state inference in drift-diffusive processes
Emir Sezik, Jacob Knight, Henry Alston +4
Splitting probabilities quantify the likelihood of particular outcomes out of a set of mutually-exclusive possibilities for stochastic processes and play a central role in first-pa…