73 citations · 117 across the 7 of their papers we have counts for
5 papers · 1 filter
Physics of selective conduction and point mutation in biological ion channels
W. A. T. Gibby, M. L. Barabash, C. Guardiani +2
We introduce a statistical and linear response theory of selective conduction in biological ion channels with multiple binding sites and possible point mutations. We derive an effe…
Quantized Dehydration and the Determinants of Selectivity in the NaChBac Bacterial Sodium Channel
O. A. Fedorenko, I. Kh. Kaufman, W. A. T. Gibby +3
A discrete electrostatic/diffusion model has been developed to describe the selective permeation of ion channels, based on ionic Coulomb blockade (ICB) and quantised dehydration (Q…
Kinetic model of selectivity and conductivity of the KcsA filter
W. A. T. Gibby, D. G. Luchinsky, I. Kh. Kaufman A. Ward +1
We introduce a self-consistent multi-species kinetic theory based on the structure of the narrow voltage-gated potassium channel. Transition rates depend on a complete energy spect…
Dynamics of ions in the selectivity filter of the KcsA channel: Towards a coupled Brownian particle description
Salvatore M. Cosseddu, Igor A. Khovanov, Michael P. Allen +3
The statistical and dynamical properties of ions in the selectivity filter of the KcsA ion channel are considered on the basis of molecular dynamics (MD) simulations of the KcsA pr…
Energetics of discrete selectivity bands and mutation-induced transitions in the calcium-sodium ion channels family
I. Kaufman, D. G. Luchinsky, R. Tindjong +2
We use Brownian dynamics simulations to study the permeation properties of a generic electrostatic model of a biological ion channel as a function of the fixed charge at its…