2 papers
stat.ME2026
Statistical Design of Pragmatic Trials Using Electronic Health Record Data when Outcome Assessments are Uncontrolled and Irregular
Jennifer F. Bobb, Sungtaek Son, Melissa L. Anderson +3
Pragmatic trials increasingly define outcomes using real-world data such as electronic health records, where assessments are collected during routine care rather than at fixed time…
stat.ME2024
Increased risk of type I errors for detecting heterogeneity of treatment effects in cluster-randomized trials using mixed-effect models
Noorie Hyun, Abisola E. Idu, Andrea J. Cook +1
Evaluating heterogeneity of treatment effects (HTE) across subgroups is common in both randomized trials and observational studies. Although several statistical challenges of HTE a…