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physics.bio-ph2026
Towards Accurate Prediction of Mutation-Induced Changes in Protein Structure
Zhuoyi Liu, Alex Calabrese, Corey S. O'Hern
Proteins can possess numerous mutations relative to their wild-type amino acid sequences with minimal impact to their structure and function. However, in other cases, even a single…
physics.bio-ph2024
Identifying the minimal sets of distance restraints for FRET-assisted protein structural modeling
Zhuoyi Liu, Alex T. Grigas, Jacob Sumner +3
Proteins naturally occur in crowded cellular environments and interact with other proteins, nucleic acids, and organelles. Since most previous experimental protein structure determ…