112 citations · 184 across the 4 of their papers we have counts for
4 papers
Exploration of methods for computing sensitivities in ODE models at dynamic and steady states
Polina Lakrisenko, Dilan Pathirana, Daniel Weindl +1
Estimating parameters of dynamic models from experimental data is a challenging, and often computationally-demanding task. It requires a large number of model simulations and objec…
pyPESTO: A modular and scalable tool for parameter estimation for dynamic models
Yannik Schälte, Fabian Fröhlich, Paul J. Jost +14
Mechanistic models are important tools to describe and understand biological processes. However, they typically rely on unknown parameters, the estimation of which can be challengi…
Dynamical models for metabolomics data integration
Polina Lakrisenko, Daniel Weindl
As metabolomics datasets are becoming larger and more complex, there is an increasing need for model-based data integration and analysis to optimally leverage these data. Dynamical…
PEtab -- interoperable specification of parameter estimation problems in systems biology
Leonard Schmiester, Yannik Schälte, Frank T. Bergmann +26
Reproducibility and reusability of the results of data-based modeling studies are essential. Yet, there has been -- so far -- no broadly supported format for the specification of p…