441 citations · 1.1k across the 11 of their papers we have counts for
12 papers
Looking forwards and backwards: dynamics and genealogies of locally regulated populations
Alison M. Etheridge, Thomas G. Kurtz, Ian Letter +2
We introduce a broad class of spatial models to describe how spatially heterogeneous populations live, die, and reproduce. Individuals are represented by points of a point measure,…
Spatial Population Genetics: It's About Time
Gideon S. Bradburd, Peter L. Ralph
Many questions that we have about the history and dynamics of organisms have a geographical component: How many are there, and where do they live? How do they move and interbreed a…
An empirical approach to demographic inference with genomic data
Peter L. Ralph
Inference with population genetic data usually treats the population pedigree as a nuisance parameter, the unobserved product of a past history of random mating. However, the histo…
Conflation of short identity-by-descent segments bias their inferred length distribution
Charleston W. K. Chiang, Peter Ralph, John Novembre
Identity-by-descent (IBD) is a fundamental concept in genetics with many applications. In a common definition, two haplotypes are said to contain an IBD segment if they share a seg…
The geography of recent genetic ancestry across Europe
Peter Ralph, Graham Coop
The recent genealogical history of human populations is a complex mosaic formed by individual migration, large-scale population movements, and other demographic events. Population…
Patterns of neutral diversity under general models of selective sweeps
Graham Coop, Peter Ralph
Two major sources of stochasticity in the dynamics of neutral alleles result from resampling of finite populations (genetic drift) and the random genetic background of nearby selec…
Is your phylogeny informative? Measuring the power of comparative methods
Carl Boettiger, Graham Coop, Peter Ralph
Phylogenetic comparative methods may fail to produce meaningful results when either the underlying model is inappropriate or the data contain insufficient information to inform the…
Stochastic population growth in spatially heterogeneous environments
Steven N. Evans, Peter L. Ralph, Sebastian J. Schreiber +1
Classical ecological theory predicts that environmental stochasticity increases extinction risk by reducing the average per-capita growth rate of populations. To understand the int…
Transcriptional regulation: Effects of promoter proximal pausing on speed, synchrony and reliability
Alistair N. Boettiger, Peter L. Ralph, Steven N. Evans
Recent whole genome polymerase binding assays have shown that a large proportion of unexpressed genes have pre-assembled RNA pol II transcription initiation complex stably bound to…
Parallel adaptation: One or many waves of advance of an advantageous allele?
Peter Ralph, Graham Coop
Our models for detecting the effect of adaptation on population genomic diversity are often predicated on a single newly arisen mutation sweeping rapidly to fixation. However, a po…
Dynamics of the time to the most recent common ancestor in a large branching population
Steven N. Evans, Peter L. Ralph
If we follow an asexually reproducing population through time, then the amount of time that has passed since the most recent common ancestor (MRCA) of all current individuals lived…
Brownian motion on disconnected sets, basic hypergeometric functions, and some continued fractions of Ramanujan
Shankar Bhamidi, Steven N. Evans, Ron Peled +1
Motivated by Lévy's characterization of Brownian motion on the line, we propose an analogue of Brownian motion that has as its state space an arbitrary closed subset of the line th…