5 papers
Rapid Polymorphic Screening using Sessile Microdroplets: Competitive Nucleation of Mannitol Polymorphs
Ruel Cedeno, Romain Grossier, Nadine Candoni +1
We developed a rapid polymorphic screening approach based on contracting sessile microdroplets which offers several advantages: (1) achieves very high supersaturation to facilitate…
Microdroplet Approach for Measuring Aqueous Solubility and Nucleation Kinetics of a Metastable Polymorph: The case of KDP Phase IV
Ruel Cedeno, Romain Grossier, Nadine Candoni +1
Solubility and interfacial energy are two fundamental parameters underlying the competitive nucleation of polymorphs. However, solubility measurement of metastable phases comes wit…
CNT effective interfacial energy and pre-exponential kinetic factor from measured NaCl crystal nucleation time distributions in contracting microdroplets
Ruel Cedeno, Romain Grossier, Nadine Candoni +3
Nucleation, the birth of a stable cluster from disorder, is inherently stochastic. Yet up to date, there are no quantitative studies on NaCl nucleation that accounts for its stocha…
Evaporation Dynamics of Sessile Saline Microdroplets in Oil
Ruel Cedeno, Romain Grossier, Nadine Candoni +2
The occurrence of concentration and temperature gradients in saline microdroplets evaporating directly in air makes them unsuitable for nucleation studies where homogeneous composi…
Nucleation in Sessile Saline Microdroplets: Induction Time Measurement via Deliquescence-Recrystallization Cycling
Ruel Cedeno, Romain Grossier, Mehdi Lagaize +4
Induction time, a measure of how long one will wait for nucleation to occur, is an important parameter in quantifying nucleation kinetics and its underlying mechanisms. Due to the…