most citedA Comprehensive Review of Emerging Approaches in Machine Learning for De Novo PROTAC Design

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cs.LG2026

TACFormer: Transformer-Based Generative Model for Target-Conditioned De Novo PROTAC Design

Yossra Gharbi, Rocío Mercado

Targeted protein degradation (TPD) represents a fundamental shift in drug discovery, moving beyond traditional target inhibition toward the event-driven removal of disease-causing…