22 citations · 39 across the 4 of their papers we have counts for
4 papers
LIMO: Latent Inceptionism for Targeted Molecule Generation
Peter Eckmann, Kunyang Sun, Bo Zhao +3
Generation of drug-like molecules with high binding affinity to target proteins remains a difficult and resource-intensive task in drug discovery. Existing approaches primarily emp…
Enhanced Diffusion and Chemotaxis of Enzymes
Mudong Feng, Michael K. Gilson
Many enzymes appear to diffuse faster in the presence of substrate and to drift either up or down a concentration gradient of their substrate. Observations of these phenomena, term…
Structure and Thermodynamics of Molecular Hydration via Grid Inhomogeneous Solvation Theory
Crystal Nguyen, Michael K. Gilson, Tom Young
Changes in hydration are central to the phenomenon of biomolecular recognition, but it has been difficult to properly frame and answer questions about their precise thermodynamic r…
Hydrosomes: Optically trapped femtoliter containers for single molecule studies and microfluidics
J. E. Reiner, A. M. Crawford, R. B. Kishore +3
We demonstrate a novel technique for creating, manipulating, and combining femtoliter volume chemical containers. Possible uses include creating controlled chemical reactions invol…