3 papers
math.PR2026
Stochastic Modelling of Telomere Length Dynamics During Hematopoiesis
Sophie Baland, Simon Toupance, Denis Villemonais
We introduce a new stochastic model of telomere length dynamics during hematopoiesis. The numerous cell divisions occurring in this setting makes telomere length dynamics, and in p…
q-bio.CB2024
Stochastic branching models for the telomeres dynamics in a model including telomerase activity
Athanase Benetos, Coralie Fritsch, Emma Horton +3
Telomeres are repetitive sequences of nucleotides at the end of chromosomes, whose evolution over time is intrinsically related to biological ageing. In most cells, with each cell…
q-bio.PE2023
A branching model for intergenerational telomere length dynamics
Athanasios Benetos, Olivier Coudray, Anne Gégout-Petit +3
We build and study an individual based model of the telomere length's evolution in a population across multiple generations. This model is a continuous time typed branching process…