2 papers
stat.ME2025
A robust score test in g-computation for covariate adjustment in randomized clinical trials leveraging different variance estimators via influence functions
Xin Zhang, Haitao Chu, Lin Liu +1
G-computation has become a widely used robust method for estimating unconditional (marginal) treatment effects with covariate adjustment in the analysis of randomized clinical tria…
stat.ME2023
Study Duration Prediction for Clinical Trials with Time-to-Event Endpoints Using Mixture Distributions Accounting for Heterogeneous Population
Hong Zhang, Jie Pu, Shibing Deng +3
In the era of precision medicine, more and more clinical trials are now driven or guided by biomarkers, which are patient characteristics objectively measured and evaluated as indi…