2 papers
stat.ME2025
Adaptive clinical trial design with delayed treatment effects using elicited prior distributions
James Salsbury, Jeremy Oakley, Steven Julious +1
Clinical trials with time-to-event endpoints, such as overall survival (OS) or progression-free survival (PFS), are fundamental for evaluating new treatments, particularly in immun…
stat.AP2023
Assurance Methods for designing a clinical trial with a delayed treatment effect
James Salsbury, Jeremy Oakley, Steven Julious +1
An assurance calculation is a Bayesian alternative to a power calculation. One may be performed to aid the planning of a clinical trial, specifically setting the sample size or to…