6 citations · 11 across the 4 of their papers we have counts for
3 papers · 1 filter
Incorporating estimands into meta-analyses of clinical trials
Antonio Remiro-Azócar, Pepa Polavieja, Emmanuelle Boutmy +9
The estimand framework is increasingly established to pose research questions in confirmatory clinical trials. In evidence synthesis, the uptake of estimands has been modest, and t…
Network Meta-Analysis of survival outcomes with non-proportional hazards using flexible M-splines
David M. Phillippo, Ayman Sadek, Hugo Pedder +1
Network meta-analysis (NMA) is widely used in healthcare decision-making, where estimates of the effect of multiple treatments on outcomes are required. For time-to-event outcomes…
Marginal and conditional summary measures: transportability and compatibility across studies
Antonio Remiro-Azócar, David M. Phillippo, Nicky J. Welton +4
Marginal and conditional summary measures do not generally coincide, have different interpretations and correspond to different decision questions. While these aspects have primari…