7 citations · 8 across the 5 of their papers we have counts for
5 papers
Understanding statistics for biomedical research through the lens of replication
Huw Llewelyn
Clinicians and scientists have traditionally focussed on whether their findings will be replicated and are very familiar with the concept. The probability that a replication study…
Adding variances of independent probability distributions to estimate probabilities of replication
Huw Llewelyn
If the prior probability distributions of all possible hypothetical true means and all possible observed means of a continuous variable are conditional on the universal set of all…
Clinical dichotomania: A major cause of over-diagnosis and over-treatment?
Huw Llewelyn
Introduction: There have been many warnings that inappropriate dichotomisation of results into positive or negative, high, or normal etc., during medical research could be very dam…
The probabilities of an outcome on intervention and control can be estimated by randomizing subjects to different testing strategies, required for assessing diagnostic tests, test trace and isolation and for natural randomisation
Huw Llewelyn
The efficacy of an intervention can be assessed by randomizing patients to different diagnostic tests instead of directly to an intervention and control. This principle is applied…
Replacing P values with frequentist posterior probabilities - as possible parameter values must have uniform base-rate prior probabilities by definition in a random sampling model
Huw Llewelyn
Possible parameter values in a random sampling model are shown by definition to have uniform base-rate prior probabilities. This allows a frequentist posterior probability distribu…