2 papers
cs.LG2026
Beyond Random Splits: Evaluating Drug-Target Affinity Models Under Chemically and Biologically Motivated Distribution Shifts Copy
Minjae Chung, Clara Li, Malar Paavai Muthukumaran +8
Drug-target affinity (DTA) prediction is widely used to prioritize candidate compounds before costly experimental screening. DTA models are often compared under a single data split…
cs.LG2026
SAGE: Agentic Framework for Interpretable and Clinically Translatable Computational Pathology Biomarker Discovery
Sahar Almahfouz Nasser, Juan Francisco Pesantez Borja, Jincheng Liu +15
Engineered image-based biomarkers offer a clinically interpretable alternative to black-box AI in computational pathology, yet their discovery remains largely intuition-driven, gui…