Urea-Mediated Solvent Reorganization of Bovine Serum Albumin in an Acid-Induced Expanded Conformation at pH 3.7

Y. Ricardo Espinosa, C. Manuel Carlevaro, C. Gaston Ferrara

Understanding the molecular mechanisms by which denaturants modulate protein structure remains a central challenge in protein biophysics. In this study, molecular dynamics (MD) sim…