4 papers
SpatialForge: Bootstrapping 3D-Aware Spatial Reasoning from Open-World 2D Images
Zishan Liu, Ruoxi Zang, Yanglin Zhang +5
Recent advancements in Large Vision-Language Models (VLMs) have demonstrated exceptional semantic understanding, yet these models consistently struggle with spatial reasoning, ofte…
Steering Protein Language Models
Long-Kai Huang, Rongyi Zhu, Bing He +1
Protein Language Models (PLMs), pre-trained on extensive evolutionary data from natural proteins, have emerged as indispensable tools for protein design. While powerful, PLMs often…
Atomas: Hierarchical Alignment on Molecule-Text for Unified Molecule Understanding and Generation
Yikun Zhang, Geyan Ye, Chaohao Yuan +5
Molecule-and-text cross-modal representation learning has emerged as a promising direction for enhancing the quality of molecular representation, thereby improving performance in v…
Annotation-guided Protein Design with Multi-Level Domain Alignment
Chaohao Yuan, Songyou Li, Geyan Ye +6
The core challenge of de novo protein design lies in creating proteins with specific functions or properties, guided by certain conditions. Current models explore to generate prote…