145 citations · 216 across the 8 of their papers we have counts for
8 papers
Deep manifold learning reveals hidden dynamics of proteasome autoregulation
Zhaolong Wu, Shuwen Zhang, Wei Li Wang +3
The 2.5-MDa 26S proteasome maintains proteostasis and regulates myriad cellular processes. How polyubiquitylated substrate interactions regulate proteasome activity is not understo…
Unsupervised cryo-EM data clustering through adaptively constrained K-means algorithm
Yaofang Xu, Jiayi Wu, Chang-Cheng Yin +1
In single-particle cryo-electron microscopy (cryo-EM), K-means clustering algorithm is widely used in unsupervised 2D classification of projection images of biological macromolecul…
A deep convolutional neural network approach to single-particle recognition in cryo-electron microscopy
Yanan Zhu, Qi Ouyang, Youdong Mao
Background: Single-particle cryo-electron microscopy (cryo-EM) has become a popular tool for structural determination of biological macromolecular complexes. High-resolution cryo-E…
Unsupervised single-particle deep clustering via statistical manifold learning
Jiayi Wu, Yong-Bei Ma, Charles Congdon +4
Motivation: Structural heterogeneity in single-particle cryo-electron microscopy (cryo-EM) data represents a major challenge for high-resolution structure determination. Unsupervis…
On the parameters affecting dual-target-function evaluation of single-particle selection from cryo-electron micrographs
Zhou Yu, Wei Li Wang, Luis R. Castillo-Menendez +2
In the analysis of frozen hydrated biomolecules by single-particle cryo-electron microscopy, template-based particle picking by a target function called fast local correlation (FLC…
Dual-target function validation of single-particle selection from low-contrast cryo-electron micrographs
Youdong Mao, Luis R. Castillo-Menendez, Joseph Sodroski
Weak-signal detection and single-particle selection from low-contrast micrographs of frozen hydrated biomolecules by cryo-electron microscopy (cryo-EM) presents a practical challen…
Dual critality of single-file transport through DNA channel
Youdong Mao, Song Chang, Shaoxuan Yang +2
This paper has been withdrawn by authors due to publication requirement.
Monte Carlo simulation of melting transition on DNA nanocompartment
Song Chang, Youdong Mao, Zhengwei Xie +2
DNA nanocompartment is a typical DNA-based machine whose function is dependent of molecular collective effect. Fundamental properties of the device have been addressed via electroc…