Exploration of the potential energy surface for the conformational interconversion of the amyloid ${\hat{I}}^2$ peptide at the fibril end

Yasuhiro Oishi, Motoharu Kitatani, Kichitaro Nakajima +2

The formation of amyloid fibrils comprising amyloid ${\hat{I}}^2$ (A${\hat{I}}^2$) peptides is associated with the pathology of Alzheimer's disease. In this study, we theoretically investigated the…