3 papers
q-bio.QM2018
A polymer model for the quantitative reconstruction of 3d chromosome architecture from Hi-C and GAM data
Guillaume Le Treut, François Képès, Henri Orland
It is widely believed that the folding of the chromosome in the nucleus has a major effect on genetic expression. For example co-regulated genes in several species have been shown…
cond-mat.soft2015
Phase behaviour of DNA in presence of DNA-binding proteins
Guillaume Le Treut, François Képès, Henri Orland
To characterize the thermodynamical equilibrium of DNA chains interacting with a solution of non-specific binding proteins, a Flory-Huggins free energy model was implemented. We ex…
q-bio.MN2006
The adaptive filter of the yeast galactose pathway
Serge Smidtas, Vincent Schachter, Francois Kepes
In the yeast Saccharomyces cerevisiae, the interplay between galactose, Gal3p, Gal80p and Gal4p determines the transcriptional status of the genes required for galactose utilizatio…