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stat.ME2026
The Modified Egger Intercept Tests for Detecting Horizontal Pleiotropy in Two-Sample Summary-Data Mendelian Randomization
Yilei Ma, Youpeng Su, Xin Liu +3
The Egger intercept (EI) test is a widely used tool to detect horizontal pleiotropy in two-sample summary-data Mendelian randomization. A significant EI test suggests that either t…
stat.ME2026
Simultaneously accounting for the winner's curse and sample structure in Mendelian randomization: bivariate rerandomized inverse variance weighted estimator
Xin Liu, Youpeng Su, Chuchu Zeng +4
The recently developed rerandomized inverse variance weighted (RIVW) estimator provides a simple and efficient framework to break the winner's curse in two-sample Mendelian randomi…