activity
20032021
most citedThe Yeast Cell-Cycle Network Is Robustly Designed

1.1k citations · 1.2k across the 9 of their papers we have counts for

collaborators

9 papers

q-bio.PE2021★ 1 cited

Model-based cellular kinetic analysis of SARS-CoV-2 infection: different immune response modes and treatment strategies

Zhengqing Zhou, Zhiheng Zhao, Shuyu Shi +10

Increasing number in global COVID-19 cases demands for mathematical model to analyze the interaction between the virus dynamics and the response of innate and adaptive immunity. He…

q-bio.CB2018★ 1 cited

Both cellular ATP level and ATP hydrolysis free energy determine energetically the calcium oscillation in pancreatic -cell

Yunsheng Sun, Congjian Ni, Yingda Ge +3

In pancreatic -cells, calcium oscillation signal is the core part of glucose-stimulated insulin secretion. Intracellular calcium concentration oscillates in response to the inta…

q-bio.CB2018

Free Energy of ATP hydrolysis manipulates the cellular calcium signals

Yingda Ge, Congjian Ni, Yunsheng Sun +1

In living cells, oscillation of the concentration of cytosolic Ca2+ is an important and pervasive signal for the intercellular and intracellular information conduction. To generate…

q-bio.MN2018★ 5 cited

Critical slowing down and attractive manifold: a mechanism for dynamic robustness in yeast cell-cycle process

Yao Zhao, Dedi Wang, Zhiwen Zhang +5

The biological processes that execute complex multiple functions, such as cell cycle, must ensure the order of sequential events and keep the dynamic robustness against various flu…

q-bio.MN2016

Phosphorylation potential and chemical fluxes govern the biological performance of multiple PdP cycles

Teng Wang, Chenzi Jin, Fangting Li

Fission yeast G2/M transition is regulated by a biochemical reaction networks which contains four components: Cdc13, Cdc2, Wee1, and Cdc25. This circuit is characterized by the ult…

q-bio.MN2013★ 4 cited

A globally attractive cycle driven by sequential bifurcations containing ghost effects in a 3-node yeast cell cycle model

Fangting Li, Mingyang Hu, Bo Zhao +3

Yeast cells produce daughter cells through a DNA replication and mitosis cycle associated with checkpoints and governed by the cell cycle regulatory network. To ensure genome stabi…