162 citations · 278 across the 3 of their papers we have counts for
6 papers
Mechanics of Pandemics
Seba Contreras, Philipp Dönges, Laura Müller +24
COVID-19 and previous pandemics have shown how diseases can disrupt, threaten, and transform daily life. Since pathogens and societies are continuously evolving, every pandemic is…
Time delay as a key to Apoptosis Induction in the p53 Network
G. Tiana, M. H. Jensen, K. Sneppen
A feedback mechanism that involves the proteins p53 and mdm2, induces cell death as a controled response to severe DNA damage. A minimal model for this mechanism demonstrates that…
Epigenetics as a first exit problem
E. Aurell, K. Sneppen
We develop a framework to discuss stability of epigenetic states as first exit problems in dynamical systems with noise. We consider in particular the stability of the lysogenic st…
Hydrogen Bonds in Polymer Folding
J. Borg, M. H. Jensen, K. Sneppen +1
The thermodynamics of a homopolymeric chain with both Van der Waals and highly-directional hydrogen bond interaction is studied. The effect of hydrogen bonds is to reduce dramatica…
Thermodynamics of Heat Shock Response
Kristine Bourke Arnvig, Steen Pedersen, Kim Sneppen
Production of heat shock proteins are induced when a living cell is exposed to a rise in temperature. The heat shock response of protein DnaK synthesis in E.coli for temperature sh…
Directed percolation with an absorbing boundary
K. B. Lauritsen, K. Sneppen, M. Markosova +1
We consider directed percolation with an absorbing boundary in 1+1 and 2+1 dimensions. The distribution of cluster lifetimes and sizes depend on the boundary. The new scaling expon…