5 papers
MedHopQA: A Disease-Centered Multi-Hop Reasoning Benchmark and Evaluation Framework for LLM-Based Biomedical Question Answering
Rezarta Islamaj, Robert Leaman, Joey Chan +13
Evaluating large language models (LLMs) in the biomedical domain requires benchmarks that can distinguish reasoning from pattern matching and remain discriminative as model capabil…
DeepER-Med: Advancing Deep Evidence-Based Research in Medicine Through Agentic AI
Zhizheng Wang, Chih-Hsuan Wei, Joey Chan +19
Trustworthiness and transparency are essential for the clinical adoption of artificial intelligence (AI) in healthcare and biomedical research. Recent deep research systems aim to…
Exploring Anti-Aging Literature via ConvexTopics and Large Language Models
Lana E. Yeganova, Won G. Kim, Shubo Tian +4
The rapid expansion of biomedical publications creates challenges for organizing knowledge and detecting emerging trends, underscoring the need for scalable and interpretable metho…
Knowledge-guided Contextual Gene Set Analysis Using Large Language Models
Zhizheng Wang, Chi-Ping Day, Chih-Hsuan Wei +9
Gene set analysis (GSA) is a foundational approach for interpreting genomic data of diseases by linking genes to biological processes. However, conventional GSA methods overlook cl…
Enhancing Biomedical Relation Extraction with Directionality
Po-Ting Lai, Chih-Hsuan Wei, Shubo Tian +2
Biological relation networks contain rich information for understanding the biological mechanisms behind the relationship of entities such as genes, proteins, diseases, and chemica…