3 papers
stat.CO2026
Observed Fisher Information in hidden Markov models - Application to a noisy Gaussian random walk
Alexandra Lefebvre, Grégory Nuel
In this work we provide analytical and closed-form expressions for the exact computation of the score and the observed Fisher information matrix in a Gaussian random walk observed…
q-bio.QM2023
An updated State-of-the-Art Overview of transcriptomic Deconvolution Methods
Bastien Chassagnol, Grégory Nuel, Etienne Becht
Although bulk transcriptomic analyses have significantly contributed to an enhanced comprehension of multifaceted diseases, their exploration capacity is impeded by the heterogeneo…
q-bio.QM2023
DeCovarT, a multidimensional probalistic model for the deconvolution of heterogeneous transcriptomic samples
Bastien Chassagnol, Grégory Nuel, Etienne Becht
Although bulk transcriptomic analyses have greatly contributed to a better understanding of complex diseases, their sensibility is hampered by the highly heterogeneous cellular com…