229 citations · 304 across the 7 of their papers we have counts for
7 papers
Learning Implicit Bias in Generative Spaces for Accelerating Protein Dynamics Emulation
Kaihui Cheng, Zhiqiang Cai, Wenkai Xiang +4
Generative emulators of protein dynamics produce plausible trajectories at a fraction of the cost of molecular dynamics, but they inherit their training distribution and tend to re…
Progress and Opportunities of Foundation Models in Bioinformatics
Qing Li, Zhihang Hu, Yixuan Wang +5
Bioinformatics has witnessed a paradigm shift with the increasing integration of artificial intelligence (AI), particularly through the adoption of foundation models (FMs). These A…
Drug Synergistic Combinations Predictions via Large-Scale Pre-Training and Graph Structure Learning
Zhihang Hu, Qinze Yu, Yucheng Guo +5
Drug combination therapy is a well-established strategy for disease treatment with better effectiveness and less safety degradation. However, identifying novel drug combinations th…
A Deep Learning Approach to Generating Photospheric Vector Magnetograms of Solar Active Regions for SOHO/MDI Using SDO/HMI and BBSO Data
Haodi Jiang, Qin Li, Zhihang Hu +8
Solar activity is usually caused by the evolution of solar magnetic fields. Magnetic field parameters derived from photospheric vector magnetograms of solar active regions have bee…
Accurate RNA 3D structure prediction using a language model-based deep learning approach
Tao Shen, Zhihang Hu, Siqi Sun +14
Accurate prediction of RNA three-dimensional (3D) structure remains an unsolved challenge. Determining RNA 3D structures is crucial for understanding their functions and informing…
Interpretable RNA Foundation Model from Unannotated Data for Highly Accurate RNA Structure and Function Predictions
Jiayang Chen, Zhihang Hu, Siqi Sun +9
Non-coding RNA structure and function are essential to understanding various biological processes, such as cell signaling, gene expression, and post-transcriptional regulations. Th…
Contrastive Cycle Adversarial Autoencoders for Single-cell Multi-omics Alignment and Integration
Xuesong Wang, Zhihang Hu, Tingyang Yu +5
Muilti-modality data are ubiquitous in biology, especially that we have entered the multi-omics era, when we can measure the same biological object (cell) from different aspects (o…