3 papers
cond-mat.stat-mech2026
Reverse engineering of mechano-kinetic parameters from stochastic force profiles in heterogeneous ensembles of molecular motors and tracks
Valentina Buonfiglio, Irene Pertici, Pasquale Bianco +2
Heterogeneity in contractile systems of molecular motors interacting with their tracks plays a key role in numerous cellular physiological and pathological processes. However, its…
cond-mat.stat-mech2024
Resolving the kinetics of an ensemble of muscle myosin motors via a temperature-dependent fitting procedure
Valentina Buonfiglio, Niccolò Zagli, Irene Pertici +3
A data fitting procedure is devised and thoroughly tested to provide self-consistent estimates of the relevant mechanokinetic parameters involved in a plausible scheme underpinning…
cond-mat.stat-mech2024
Force and kinetics of fast and slow muscle myosin determined with a synthetic sarcomere-like nanomachine
Valentina Buonfiglio, Irene Pertici, Matteo Marcello +7
Myosin II is the muscle molecular motor that works in two bipolar arrays in each thick filament of the striated (skeletal and cardiac) muscle, converting the chemical energy into s…