2 papers
cs.LG2026
ProMeta: Few-shot PROTAC-targeted degradation prediction across E3 ligases
Yuansheng Liu, Yufei Ye, Tao Tang +3
Proteolysis-targeting chimeras (PROTACs) have emerged as a transformative therapeutic strategy that selectively degrades historically ''undruggable'' targets via the ubiquitin-prot…
cs.CL2024
Instruction Multi-Constraint Molecular Generation Using a Teacher-Student Large Language Model
Peng Zhou, Jianmin Wang, Chunyan Li +11
While various models and computational tools have been proposed for structure and property analysis of molecules, generating molecules that conform to all desired structures and pr…