2 papers
q-bio.BM2026
Learning Protein Structure-Function Relationships through Knowledge-guided Representation Decomposition
Mingqing Wang, Zhiwei Nie, Athanasios V. Vasilakos +2
Proteins encode diverse functions within complex three-dimensional structures, yet most deep learning representations remain highly entangled, obscuring the biophysical signals tha…
q-bio.BM2024
ProtFAD: Introducing function-aware domains as implicit modality towards protein function prediction
Mingqing Wang, Zhiwei Nie, Yonghong He +2
Protein function prediction is currently achieved by encoding its sequence or structure, where the sequence-to-function transcendence and high-quality structural data scarcity lead…