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math.OC2026
Optimal chemo-immunotherapy scheduling: A hybrid QPSO-SQP approach with Michaelis-Menten pharmacodynamics
Bereket Sitotaw Kidane, Md Samiul Haque Motayed, Shuo Wang
Optimal scheduling of combined chemo-immunotherapy is often formulated as a control-affine optimal control problem, which generically yields boundary-selected (bang-bang-type) prot…
math.OC2026★ 1 cited
Optimal Control for Cancer Chemotherapy Using Hybrid Quantum Particle Swarm Optimization
Bereket Sitotaw Kidane, Md Samiul Haque Motayed, Shuo Wang
Optimal control in cancer chemotherapy is challenged by tumor heterogeneity and mutations, which complicate treatment effectiveness. Traditional methods, such as Pontryagin's maxim…