14 papers
Testing Additivity in Lead and Benzo[a]pyrene-induced Neurodegeneration in Caenorhabditis elegans
Niccolo Anceschi, Javier Huayta, Joel N. Meyer +2
Exposure to environmental contaminants is a recognized cause of neurotoxicity, contributing to the onset of a broad range of neurological conditions. In realistic settings, such ex…
Local graph estimation with pathwise false discovery control
Omar Melikechi, David B. Dunson, Noureddine Melikechi +1
Many datasets include a small set of variables, such as biomarkers or clinical outcomes, whose relationships to the broader system are of primary scientific interest. Estimating th…
Spectral decomposition-assisted multi-study factor analysis
Lorenzo Mauri, Niccolò Anceschi, David B. Dunson
This article focuses on covariance estimation for multi-study data. Popular approaches employ factor-analytic terms with shared and study-specific loadings that decompose the varia…
Leveraging ontologies to predict biological activity of chemicals across genes
Jennifer N. Kampe, David B. Dunson, Celeste K. Carberry +3
High-throughput screening (HTS) is useful for evaluating chemicals for potential human health risks. However, given the extraordinarily large number of genes, assay endpoints, and…
Blessing of dimension in Bayesian inference on covariance matrices
Shounak Chattopadhyay, Anru R. Zhang, David B. Dunson
Bayesian factor analysis is routinely used for dimensionality reduction in modeling of high-dimensional covariance matrices. Factor analytic decompositions express the covariance a…
Link prediction in ecological networks under extreme taxonomic bias
Jennifer N. Kampe, Camille M. M. DeSisto, David B. Dunson
Ecological networks offer powerful insights into community function, but without first characterizing these networks accurately, our ability to detect and interpret changes under e…