45 citations · 62 across the 5 of their papers we have counts for
5 papers
Counterions in RNA structure: Structural bioinformatics analysis to identify the role of Mg2+ ions in base pair formation
Swati Adhikari, Dhananjay Bhattacharyya, Parthajit Roy
Contribution of metal ions on nucleic acids structures and functions is undeniable. Among the available metal ions like Na+, K+, Ca2+, Mg2+ etc., the role that play the Mg2+ ion is…
Maturation of siRNA by strand separation: Steered Molecular dynamics study
Rakesh K Mishra, Sanchita Mukherjee, Dhananjay Bhattacharyya
RNA interference, particularly siRNA induced gene silencing is becoming an important avenue of modern therapeutics. The siRNA is delivered to the cells as short double helical RNA…
Unraveling siRNA Unzipping Kinetics with Graphene
Santosh Mogurampelly, Swati Panigrahi, Dhananjay Bhattacharyya +2
Using all atom molecular dynamics simulations, we report spontaneous unzipping and strong binding of small interfering RNA (siRNA) on graphene. Our dispersion corrected density fun…
Unzipping and binding of small interfering RNA with single walled Carbon Nanotube: a platform for small interfering RNA delivery
Mogurampelly Santosh, Swati Panigrahi, Dhananjay Bhattacharyya +2
In an effort to design efficient platform for siRNA delivery, we combine all atom classical and quantum simulations to study the binding of small interfering RNA (siRNA) by pristin…
Equilibrium study of Protein/DNA Complexes from Crystal Structure Data
Sudipta Samanta, J. Chakrabarti, Dhananjay Bhattacharyya
From the crystal structure data and using the concept of equilbrium statistical mechanics we show how to calculate the thermodynamics of protein/DNA complexes. We apply the method…