93 citations · 140 across the 5 of their papers we have counts for
3 papers · 1 filter
Accelerating flux balance calculations in genome-scale metabolic models by localizing the application of loopless constraints
Siu Hung Joshua Chan, Lin Wang, Satyakam Dash +1
Background: Genome-scale metabolic network models and constraint-based modeling techniques have become important tools for analyzing cellular metabolism. Thermodynamically infeasib…
Large-scale inference and graph theoretical analysis of gene-regulatory networks in B. stubtilis
C. Christensen, A. Gupta, C. D. Maranas +1
We present the methods and results of a two-stage modeling process that generates candidate gene-regulatory networks of the bacterium B. subtilis from experimentally obtained, yet…
Elucidation of Directionality for Co-Expressed Genes: Predicting Intra-Operon Termination Sites
Anshuman Gupta, Costas D. Maranas, Reka Albert
We present a novel framework for inferring regulatory and sequence-level information from gene co-expression networks. The key idea of our methodology is the systematic integration…