30 papers
DUET: Dual-Paradigm Adaptive Expert Triage with Single-cell Inductive Prior for Spatial Transcriptomics Prediction
Junchao Zhu, Ruining Deng, Junlin Guo +11
Inferring spatially resolved gene expression from histology images offers a cost-effective complement to spatial transcriptomics (ST). However, existing methods reduce this task to…
Explainable Pathomics Feature Visualization via Correlation-aware Conditional Feature Editing
Yuechen Yang, Junlin Guo, Ruining Deng +9
Pathomics is a recent approach that offers rich quantitative features beyond what black-box deep learning can provide, supporting more reproducible and explainable biomarkers in di…
SCR2-ST: Combine Single Cell with Spatial Transcriptomics for Efficient Active Sampling via Reinforcement Learning
Junchao Zhu, Ruining Deng, Junlin Guo +13
Spatial transcriptomics (ST) is an emerging technology that enables researchers to investigate the molecular relationships underlying tissue morphology. However, acquiring ST data…
Patient-Conditioned Adaptive Offsets for Reliable Diagnosis across Subgroups
Gelei Xu, Yuying Duan, Jun Xia +3
AI models for medical diagnosis often exhibit uneven performance across patient populations due to heterogeneity in disease prevalence, imaging appearance, and clinical risk profil…
From Classification to Cross-Modal Understanding: Leveraging Vision-Language Models for Fine-Grained Renal Pathology
Zhenhao Guo, Rachit Saluja, Tianyuan Yao +13
Fine-grained glomerular subtyping is central to kidney biopsy interpretation, but clinically valuable labels are scarce and difficult to obtain. Existing computational pathology ap…
DeepAndes: A Self-Supervised Vision Foundation Model for Multi-Spectral Remote Sensing Imagery of the Andes
Junlin Guo, James R. Zimmer-Dauphinee, Jordan M. Nieusma +16
By mapping sites at large scales using remotely sensed data, archaeologists can generate unique insights into long-term demographic trends, inter-regional social networks, and past…