175 citations · 254 across the 10 of their papers we have counts for
5 papers · 1 filter
On the effects of alternative optima in context-specific metabolic model predictions
Semidán Robaina-Estévez, Zoran Nikoloski
Recent methodological developments have facilitated the integration of high-throughput data into genome-scale models to obtain context-specific metabolic reconstructions. A unique…
Control principles of metabolic networks
Georg Basler, Zoran Nikoloski, Abdelhalim Larhlimi +2
Deciphering the control principles of metabolism and its interaction with other cellular functions is central to biomedicine and biotechnology. Yet, understanding the efficient con…
Assessing the significance of knockout cascades in metabolic networks
Oriol Güell, Francesc Sagués, Georg Basler +2
Complex networks have been shown to be robust against random structural perturbations, but vulnerable against targeted attacks. Robustness analysis usually simulates the removal of…
On the relation between reactions and complexes of (bio)chemical reaction networks
Jost Neigenfind, Sergio Grimbs, Zoran Nikoloski
Robustness of biochemical systems has become one of the central questions in systems biology although it is notoriously difficult to formally capture its multifaceted nature. Maint…
Biochemical network decomposition reveals absolute concentration robustness
Jost Neigenfind, Sergio Grimbs, Zoran Nikoloski
Robustness of biochemical systems has become one of the central questions in Systems Biology, although it is notoriously difficult to formally capture its multifaceted nature. Main…