3 papers
cs.LG2026
ContextFlow: Context-Aware Flow Matching For Trajectory Inference From Spatial Omics Data
Santanu Subhash Rathod, Francesco Ceccarelli, Sean B. Holden +3
Inferring trajectories from longitudinal spatially-resolved omics data is fundamental to understanding the dynamics of structural and functional tissue changes in development, rege…
cs.CV2025
HistoWAS: A Pathomics Framework for Large-Scale Feature-Wide Association Studies of Tissue Topology and Patient Outcomes
Yuechen Yang, Junlin Guo, Yanfan Zhu +10
High-throughput "pathomic" analysis of Whole Slide Images (WSIs) offers new opportunities to study tissue characteristics and for biomarker discovery. However, the clinical relevan…
q-bio.QM2025
Robust multicellular programs dissect the complex tumor microenvironment and track disease progression in colorectal adenocarcinomas
Loan Vulliard, Teresa Glauner, Sven Truxa +8
Colorectal cancer (CRC) is highly heterogeneous, with five-year survival rates dropping from 90% in localized disease to 15% with distant metastases. Disease progressio…