432 citations · 1.8k across the 37 of their papers we have counts for
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Imaging proteins at the truly single-molecule level
Jean-Nicolas Longchamp, Stephan Rauschenbach, Sabine Abb +4
Imaging single proteins has been a long-standing ambition for advancing various fields in natural science, as for instance structural biology, biophysics and molecular nanotechnolo…
Low-energy electron holographic imaging of individual tobacco mosaic virions
Jean-Nicolas Longchamp, Tatiana Latychevskaia, Conrad Escher +1
Modern structural biology relies on NMR, X-ray crystallography and cryo-electron microscopy for gaining information on biomolecules at nanometer, sub-nanometer or atomic resolution…
Coherent diffraction and holographic imaging of individual biomolecules using low-energy electrons
Tatiana Latychevskaia, Jean-Nicolas Longchamp, Conrad Escher +1
Modern microscopy techniques are aimed at imaging an individual molecule at atomic resolution. Here we show that low-energy electrons with kinetic energies of 50-250 eV offer a pos…
Non-destructive imaging of an individual protein
Jean-Nicolas Longchamp, Tatiana Latychevskaia, Conrad Escher +1
The mode of action of proteins is to a large extent given by their ability to adopt different conformations. This is why imaging single biomolecules at atomic resolution is one of…
Non-destructive Imaging of Individual Bio-Molecules
Matthias Germann, Tatiana Latychevskaia, Conrad Escher +1
Radiation damage is considered to be the major problem that still prevents imaging an individual biological molecule for structural analysis. So far, all known mapping techniques u…