76 citations · 305 across the 18 of their papers we have counts for
3 papers · 1 filter
Modeling the Effect of Blunt Impact on Mitochondrial Dysfunction in Cartilage
Georgi I. Kapitanov, Bruce P. Ayati, James A. Martin
Mounting evidence for the role of oxidative stress in the degeneration of articular cartilage after an injurious impact requires our modeling & simulation efforts to temporarily sh…
Modeling the Effects of Multiple Myeloma on Kidney Function
Julia C. Walk, Bruce P. Ayati, Sarah A. Holstein
Multiple myeloma (MM), a plasma cell cancer, is associated with many health challenges, including damage to the kidney by tubulointerstitial fibrosis. We develop a mathematical mod…
Linking Cellular and Mechanical Processes in Articular Cartilage Lesion Formation: A Mathematical Model
Georgi I. Kapitanov, Xiayi Wang, Bruce P. Ayati +2
A severe application of stress on articular cartilage can initiate a cascade of biochemical reactions that can lead to the development of osteoarthritis. We constructed a multiscal…